What is RADSEG™ Method?
RADSEG™ Method is a minimally invasive technique where radiation is delivered specifically to the affected area of the liver in a way that mimics the curative effects of a surgical resection (removal of part of the liver) or ablation but without the need for an operation. The goal is to destroy the tumor in its entirety while minimizing damage to the surrounding healthy liver tissue.
Use of Yttrium Microspheres
Yttrium-90 (Y-90) microspheres are tiny beads that contain the radioactive isotope yttrium-90. These microspheres are typically used in a procedure called selective internal radiation therapy (SIRT), or radioembolization, which is a form of internal radiation therapy. The beads are delivered directly into the blood vessels that feed the liver tumor.
How it Works
Large liver tumor candidate for RADLOBE™ Method
Localization with mapping procedure.
Confirmation after treatment with RADLOBE™ Method
Excellent results after RADLOBE™ Method
Advantages of Yttrium Microspheres
Localized Treatment
The radiation is delivered directly to the tumor, minimizing damage to the healthy liver and surrounding structures.
Minimally Invasive
Unlike traditional surgery, this procedure is minimally invasive, requiring only a small incision or catheter insertion
Suitable for Inoperable Tumors
For patients whose liver cancer is not amenable to surgical resection, liver transplantation, or ablation, RADSEG™ can provide a therapeutic option.
Effective for Large Tumors
It is often used for tumors up to 6-8 cm that can be isolated by an angiogram and therefore cured with focal, precise radiotherapy.
How it Works
Mapping and Planning
The first step involves imaging (such as CT or angiography) to map the liver’s blood supply and locate the focal tumor. This step is crucial to ensure that the radiation will target the tumor precisely and effectively.
Delivery of Yttrium Microspheres
A catheter is inserted into an artery (usually through the femoral artery in the groin) and threaded up to the liver, specifically and selectively to the blood vessels supplying the tumor. The yttrium microspheres are then injected very selectively using the RADSEG™ method very selectively directly into the artery of the tumor. Because tumors in the liver often have their own blood supply, the microspheres become trapped in the vessels, delivering a high dose of radiation directly to the tumor.
Radiation Effect
Yttrium-90 is a beta-emitting radioisotope. As the microspheres lodge in the blood vessels feeding the tumor, the radiation emitted by the yttrium-90 destroys the cancer while not affecting the remainder of the liver tissue.
Potential Benefits
Potential Curative Effect
For certain patients, radioembolization with RADSEG™ method Yttrium-90 microspheres for localized tumors can possibly cure patients of their cancer.
Symptom Control
It can reduce symptoms related to a liver tumor, such as pain and discomfort.
Tumor Shrinkage
It can completely shrink small tumors and obviate the need for surgery, transplantation or ablation in the future in some cases.
Who is a Candidate?
Patients who may benefit from RADSEG™ with yttrium microspheres include:
Our Candidate
Those with localized tumor that cannot be ablated or resected due to its size, location, adjacency to critical structures, or the patient’s liver function.
Individuals who are not candidates for liver transplantation but still have liver cancer that can be treated effectively with localized RADSEG™ Method.
Conclusion
RADSEG™ Method using yttrium-90 microspheres is an innovative and effective treatment for liver cancer, particularly for patients with localize disease who are not candidates for ablation or resection. By delivering focal targeted radiation directly to liver tumors, it offers a way to treat cancer with the potential for cures, in a manner that preserves quality of life.
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